Characterization of pentamidine excretion in the isolated perfused rat kidney
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چکیده
منابع مشابه
Characterization of pentamidine excretion in the isolated perfused rat kidney.
OBJECTIVE To study the renal excretion and kidney accumulation of pentamidine, a potentially nephrotoxic compound, in the isolated perfused rat kidney (IPK). MATERIALS AND METHODS IPK experiments (3-4 per treatment group) were conducted using male Sprague-Dawley rats (250-350 g). Dose proportionality studies were carried out over a pentamidine dosing range of 80-4000 microg, designed to targe...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2003
ISSN: 1460-2091
DOI: 10.1093/jac/dkg341